Detalhe da pesquisa
1.
Genetics of Common, Complex Coronary Artery Disease.
Cell
; 177(1): 132-145, 2019 03 21.
Artigo
Inglês
| MEDLINE | ID: mdl-30901535
2.
Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood.
Cell
; 177(3): 587-596.e9, 2019 04 18.
Artigo
Inglês
| MEDLINE | ID: mdl-31002795
3.
GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis.
Cell
; 179(6): 1276-1288.e14, 2019 11 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31778654
4.
A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression.
Cell
; 170(3): 522-533.e15, 2017 Jul 27.
Artigo
Inglês
| MEDLINE | ID: mdl-28753427
6.
Genetics of human cardiovascular disease.
Cell
; 148(6): 1242-57, 2012 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-22424232
7.
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.
Nature
; 593(7859): 429-434, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34012082
8.
A brief history of human disease genetics.
Nature
; 577(7789): 179-189, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31915397
9.
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells.
Nature
; 586(7831): 769-775, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33057200
10.
A structural variation reference for medical and population genetics.
Nature
; 581(7809): 444-451, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32461652
11.
Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease.
PLoS Genet
; 18(9): e1010294, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36048760
12.
Efficacy and Safety of an Investigational Single-Course CRISPR Base-Editing Therapy Targeting PCSK9 in Nonhuman Primate and Mouse Models.
Circulation
; 147(3): 242-253, 2023 01 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36314243
13.
Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study.
Hum Mol Genet
; 31(20): 3566-3579, 2022 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35234888
14.
New Approaches for Targeting PCSK9: Small-Interfering Ribonucleic Acid and Genome Editing.
Arterioscler Thromb Vasc Biol
; 43(7): 1081-1092, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37259866
15.
Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.
PLoS Genet
; 17(4): e1009503, 2021 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-33822779
16.
Non-parametric Polygenic Risk Prediction via Partitioned GWAS Summary Statistics.
Am J Hum Genet
; 107(1): 46-59, 2020 07 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32470373
17.
Coronary Disease Association With ADAMTS7 Is Due to Protease Activity.
Circ Res
; 129(4): 458-470, 2021 08 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34176299
18.
Genetics of coronary artery disease: discovery, biology and clinical translation.
Nat Rev Genet
; 18(6): 331-344, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28286336
19.
Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity.
Nature
; 544(7649): 235-239, 2017 04 12.
Artigo
Inglês
| MEDLINE | ID: mdl-28406212
20.
A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.
PLoS Genet
; 16(4): e1008629, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32282858